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KMID : 0362220120390030191
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Journal of The Korean Research Society for Dental Materials
2012 Volume.39 No. 3 p.191 ~ p.198
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Surface Modification of Titanium Implant by Anodic Oxidation Treatment and Bisphosphate Immobilization
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Kim Won-Gi
Lee Seung-Jae
Oh Eun-Ju
Park Il-Song
Lee Min-Ho
Oh Kwi-Ok
Kim Hyung-Seop
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Abstract
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This study was carried out to examine the effect of bisphosphonates (BPs) on the nanotubular titanium surface in vitro and vivo. Samples were divided into three groups: (1) machine-turned (MT), (2) anodized and heat-treated (AH), and (3) anodized, heat- and ibandronate-treated (AHI). Compared to MT group, the ALP activity was 100.17±1.74% in AH group and 109.25±4.52% in AHI group, with statistical significant differences between AHI and other two groups (P<0.05). Also, AHI group (17.9±2.5) showed the highest removal torque (N·cm) at 4 weeks, followed in order by AH group (14.5±1.8), and MT group (5.8±0.8), with statistical significant differences between MT and the other two groups. Within the limits of this
experiment, these results provide new evidence that immobilized BPs have positive effects on osseointegration of nanotubular titanium implant.
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KEYWORD
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anodic oxidation, titanium implant, titania nanotube, removal torque, bisphosphonates
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